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The Gene by Siddhartha Mukherjee
The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). "Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself." –Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).
Molecular Biology Of The Cell by Bruce Alberts
This volume, written by renowned experts, provides complete coverage of the main genetic conditions associated with diabetes. Divided into five sections, it offers insights into genetic defects involving the pancreatic beta cell, extreme insulin resistance, ciliopathies, obesity and glucose metabolism, chromosomal defects, and other genetic conditions associated with increased susceptibility to diabetes. Other topics include the various subtypes of monogenic diabetes, such as the neonatal form and the Wolfram syndrome, as well as chromosomal defects leading to complex conditions affiliated with diabetes, like Trisomy 21 or Prader-Willi syndrome. There are also chapters dedicated to the poorly explored relationships between metabolism and neurodegenerative disorders like Friedreich’s ataxia and muscular dystrophy. This book is a reference for every pediatric and adult endocrinologist and diabetologist, even experienced ones, with an interest in the intricacies and protean aspects of disorders of glucose metabolism secondary to genetic diseases.
The Gene Bomb by David E. Comings
Have you ever wondered by in recent years there seems to be an increase in the number of children and adults with attention deficit disorder, depression, learning disabilities, autism, and anxiety. Dr. Comings proposes a provocative new theory in which the delaying of childbearing in those with longer periods of education indirectly results in the selection of genes for these disorders.
The Selfish Gene by Charles Simonyi Professor of the Public Understanding of Science Richard Dawkins
An ethologist shows man to be a gene machine whose world is one of savage competition and deceit
Evolution By Gene Duplication by Susumu Ohno
It is said that "necessity is the mother of invention". To be sure, wheels and pulleys were invented out of necessity by the tenacious minds of upright citi zens. Looking at the history of mankind, however, one has to add that "Ieisure is the mother of cultural improvement". Man's creative genius flourished only when his mind, freed from the worry of daily toils, was permitted to entertain apparently useless thoughts. In the same manner, one might say with regard to evolution that "natural selection mere(y tnodifted, while redundanry created". Natural selection has been extremely effective in policing alleHe mutations which arise in already existing gene loci. Because of natural selection, organisms have been able to adapt to changing environments, and by adaptive radiation many new species were created from a common ancestral form. Y et, being an effective policeman, natural selection is extremely conservative by nature. Had evolution been entirely dependent upon natural selection, from a bacterium only numerous forms of bacteria would have emerged. The creation of metazoans, vertebrates and finally mammals from unicellular organisms would have been quite impos sible, for such big leaps in evolution required the creation of new gene loci with previously nonexistent functions. Only the cistron which became redun dant was able to escape from the relentless pressure of natural selection, and by escaping, it accumulated formerly forbidden mutations to emerge as a new gene locus.
Crash Course Cell Biology And Genetics E Book by Matthew Stubbs
The new series of Crash Course continues to provide readers with complete coverage of the MBBS curriculum in an easy-to-read, user-friendly manner. Building on the success of previous editions, the new Crash Courses retain the popular and unique features that so characterised the earlier volumes. All Crash Courses have been fully updated throughout. More than 180 illustrations present clinical, diagnostic and practical information in an easy-to-follow manner Friendly and accessible approach to the subject makes learning especially easy Written by students for students - authors who understand exam pressures Contains ‘Hints and Tips’ boxes, and other useful aide-mémoires Succinct coverage of the subject enables ‘sharp focus’ and efficient use of time during exam preparation Contains a fully updated self-assessment section - ideal for honing exam skills and self-testing Self-assessment section fully updated to reflect current exam requirements Contains ‘common exam pitfalls’ as advised by faculty Crash Courses also available electronically! Online self-assessment bank also available - content edited by Dan Horton-Szar!
Advances In Artificial Life by European Conference on Artificial Life
This volume contains 71 revised refereed papers, including seven invited surveys, presented during the Third European Conference on Artificial Life, ECAL '95, held in Granada, Spain in June 1995. Originally AL was concerned with applying biologically inspired solutions to technology and with examining computational expertise in order to reproduce and understand life processes. Despite its short history, AL now is becoming a mature scientific field. The volume reports the state of the art in this exciting area of research; there are sections on foundations and epistemology, origins of life and evolution, adaptive and cognitive systems, artificial worlds, robotics and emulation of animal behavior, societies and collective behavior, biocomputing, and applications and common tools.
Intelligent Systems For Engineers And Scientists by Adrian A. Hopgood
The third edition of this bestseller examines the principles of artificial intelligence and their application to engineering and science, as well as techniques for developing intelligent systems to solve practical problems. Covering the full spectrum of intelligent systems techniques, it incorporates knowledge-based systems, computational intelligence, and their hybrids. Using clear and concise language, Intelligent Systems for Engineers and Scientists, Third Edition features updates and improvements throughout all chapters. It includes expanded and separated chapters on genetic algorithms and single-candidate optimization techniques, while the chapter on neural networks now covers spiking networks and a range of recurrent networks. The book also provides extended coverage of fuzzy logic, including type-2 and fuzzy control systems. Example programs using rules and uncertainty are presented in an industry-standard format, so that you can run them yourself. The first part of the book describes key techniques of artificial intelligence—including rule-based systems, Bayesian updating, certainty theory, fuzzy logic (types 1 and 2), frames, objects, agents, symbolic learning, case-based reasoning, genetic algorithms, optimization algorithms, neural networks, hybrids, and the Lisp and Prolog languages. The second part describes a wide range of practical applications in interpretation and diagnosis, design and selection, planning, and control. The author provides sufficient detail to help you develop your own intelligent systems for real applications. Whether you are building intelligent systems or you simply want to know more about them, this book provides you with detailed and up-to-date guidance. Check out the significantly expanded set of free web-based resources that support the book at: http://www.adrianhopgood.com/aitoolkit/