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Parasitic Infections In The Compromised Host by Peter D. Walzer
The first in a new series created to acknowledge the explosion of knowledge in fields related to infectious disesases and clinical microbiology. Thirteen contributions focus on organisms which are of major medical importance in this country or which have contributed to an understanding of pathology.
Clinical Approach To Infection In The Compromised Host by Robert H. Rubin
At the beginning of the new millennium, it is opportune to raveling of the molecular pathways of impaired host - review what has been accomplished in the field of infec- fense mechanisms and the characterization of the genetic tious diseases during the last decades of the previous mutations involved, with the prospect of novel strategies century. The paradigm of the immunocompromised host for therapeutic interventions and possible corrective gene has taught much about the pathophysiology of infectious therapy. In this foreword, I will take a helicopter view of diseases, particularly with regard to immunological as- the various aspects of host defense mechanisms with pects of host defense. In the beginning, Robert Good special emphasis on genetic factors, because of their re- called immunodeficiency syndromes “experiments of na- vance for the course and outcome of infections. ture. ” In the 1960s and subsequent decades, the clinical During life, there exist phases of age-related c- and immunological aspects of immune deficiencies were promised immune functions. After birth there is a phys- studied and adequate treatment attempted. A reflection of logical immune deficiency because the production of an- these developments were the three successful meetings on bodies commences slowly upon contact of the neonate these topics in Veldhoven, The Netherlands (1980), Stir- with microorganisms and upon vaccination.
"Infection in the Compromised Host" has become a classic chapter in textbooks devoted to infectious diseases and internal medicine. The numbers of compromised hosts are increasing in the era of modem medicine because of our expanded capabilities to deal with difficult diseases, especially neoplasms. As a consequence, microbiologic complications related to the intensive care administered to these patients are increasing as well. Under these circum stances, not only does the underlying illness create conditions favorable for the development of unusual infections, but often the therapy contributes to the acquisition of potential pathogens that turn into agents responsible for severe and frequently fatal disease. Granulocytopenia and immunosuppression have been the two key fac tors in predisposing patients with cancer and other serious diseases to severe bacterial infections. Colonization by hospital-acquired pathogens and breaks in the anatomic barriers-as a result of disease or medical intervention-have contributed to the high incidence of infectious diseases in these patients. Although there is some overlap between the types of infection in granulocytopenic and immunosuppressed hosts, each ofthese clinical entities has distinctive features thatjustify considering them separately, reserving the term immunocompromised hosts only when refer ring to patients who are predisposed to opportunistic infections. For about two decades, infections in granulocytopenic patients have attracted the atten tion of clinicians because they represent a model for the study of antimicrobial drugs in hosts deprived of an essential element of defense against bacterial infection, that is, an adequate number of normally functioning granulocytes.
Hospital Associated Infections In The Compromised Host by Gerald P. Bodey
Henry S Clinical Diagnosis And Management By Laboratory Methods E Book by Richard A. McPherson
Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test selection and interpretation of results. Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! A user-friendly full-color layout puts all the latest, most essential knowledge at your fingertips. Update your understanding of the scientific foundation and clinical application of today's complete range of laboratory tests. Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection. Reference the information you need quickly and easily thanks to a full-color layout, many new color illustrations and visual aids, and an organization by organ system. Master all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke disorders; coagulation testing for antiplatelet drugs such as aspirin and clopidogrel; biochemical markers of bone metabolism; clinical enzymology; hematology and transfusion medicine; medical microbiology; body fluid analysis; and many other rapidly evolving frontiers in the field. Effectively monitor the pace of drug clearing in patients undergoing pharmacogenomic treatments with a new chapter on this groundbreaking new area. Apply the latest best practices in clinical laboratory management with special chapters on organization, work flow, quality control, interpretation of results, informatics, financial management, and establishing a molecular diagnostics laboratory. Confidently prepare for the upcoming recertification exams for clinical pathologists set to begin in 2016.
Flukes And Snails Revisited by D. Rollinson
Summarises the current state of various studies investigating snail-parasite relationships.
Concomitant Infections by F. E. G. Cox
Explores the interactions between parasites and other infectious agents, with particular emphasis on immunological and ecological aspects.
Manual Of Commercial Methods In Clinical Microbiology by Allan L. Truant
A general resource for all subdisciplines of clinical microbiology to use when evaluating commercial methods, tests, or procedures. • Reviews all the commercially available tests (both manual and automated) in the discipline of clinical microbiology. • Includes a description of the sensitivities, specificities, and predictive values from peer-reviewed sources. • Features separate chapters devoted to molecular microbiology, information management, emerging infectious diseases, and veterinary clinical microbiology.
Transplant Infections by Raleigh A. Bowden
Transplant Infections is a practical, clinically focused reference covering the common and more unusual bacterial, viral, and fungal infections affecting patients who have received stem cell or solid organ transplants. It provides a comprehensive review of the epidemiology, diagnosis, and management of opportunistic infections and presents strategies for infection prevention and control. Highlights of the Third Edition include a chapter on new immunosuppressive agents and expanded coverage of tropical infections and West Nile virus.