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Current Advances In Osteosarcoma by Eugenie S. Kleinerman, M.D.
Current Advances in Osteosarcoma edited by Dr. Eugenie S. Kleinerman summarizes molecular and genetic characteristics, new therapeutic ideas, and biological characteristics that have been uncovered in the past 10 years. Osteosarcoma is an aggressive malignant neoplasm and it is also the most common histological form of bone cancer. It accounts for approximately 56% of new bone tumors, making it the most primary malignant bone tumor in children and adolescents. The lungs are the most common site of metastases and once osteosarcoma spreads to the lungs, it is very difficult to treat. To improve the outcome of this disease, the biology of osteosarcoma needs to be better understood. There are numerous investigators around the world who have made seminal discoveries about the important molecular pathways and genetic alterations that contribute to the development and metastases of osteosarcoma. Other investigators have proposed novel therapeutic strategies including some based on the molecular and genetic phenotype of the disease. Current Advances in Osteosarcoma summarizes all of these new discoveries in one singular text, which will help move the field forward.
Rescue On The Rio Lilah Book 2 In Finding Home Series by Verna Clay
Finding Home Series: Cry of the West: Hallie Rescue on the Rio: Lilah Missouri Challenge: Daisy Rush Garrett has been hired by his friends, Cooper and Hallie Jerome (book one), to find Hallie's sister, Lilah, and persuade her to return to Oregon with him. The sisters parted ways twenty years earlier and Hallie longs to be reunited with her only sibling. Lilah Parker yearns for her family, but in her infrequent letters to her sister Hallie, she has lied about her occupation. Her sister believes her to be a seamstress, when, in truth, she is a wealthy man's mistress. Lilah's shame and fear that she will be disowned by her loved ones causes her to reject Rush's offer of escort to Oregon. However, fate has other plans for these mismatched lovers as they travel from New Orleans to the Willamette Valley in Oregon. Oh, and along the way, Lilah gets kidnapped by bandits. The book can be read as a standalone.
Malignant Pleural Mesothelioma by Ken O'Byrne
Malignant pleural mesothelioma, a malignancy due largely to asbestos exposure, represents an increasingly common challenge to clinical and medical oncologists, respiratory physicians, and cardiothoracic surgeons, as well as researchers in the field. The disease has yet to reach its peak and is expected to kill over 100,000 people worldwide. As malignant pleural mesothelioma gains in profile, Kenneth O'Byrne and Valerie Rusch present a comprehensive overview of the subject, aimed at all health care professionals who come into contact with patients with the disease. The book includes chapters on epidemiology, diagnosis, histopathology, radiology, surgery, chemotherapy, immune therapy, radiotherapy, and palliative medicine, written by an international team of contributors. A molecular biology section focuses on the carcinogenic effects of asbestos fibres and simian virus 40, angiogenesis and angiogenic growth factors, the immune response, and genetic abnormalities detected inthe disease. Future therapies are also covered, as is a perspective on the distinct legal issues related to the disease. This highly-illustrated, full colour book provides the ultimate, timely resource on this devastating disease.
Willmington S Guide To The Bible by H. L. Willmington
WILLMINGTON'S GUIDE TO THE BIBLE is a treasury of Bible knowledge written in layman's language. Dr. Willmington's goal has been to publish a concise, all-inclusive summary of basic Bible information in one volume, to make available in abbreviated form "a complete Bible education in a single book.
In Search Of Eden The Second Chances Collection Book 2 by Linda Nichols
More Heart-Gripping Fiction From Bestselling Author Linda Nichols A girl who has never been able to settle down, Miranda begins various adventures, but whenever reality begins to tarnish her dreams, she gives up. As she approaches her twenty-seventh birthday, she determines to reinvent her life. But there's one loose end to tie down first... Joseph Williams, the chief of police in Abingdon, Virginia, always tries to do what is right, to perform his duty and protect those he loves. He becomes suspicious of the new woman in town, and after checking further, he discovers she has no history. Then he finds a baby picture of his niece in her possession... In Search of Eden is a story about law and grace, about forgiveness and redemption, about finding joy and rest in a broken world.
Red 1 2 3 by John Katzenbach
A psycho turns fairy-tale endings into nightmares in this “vivid cat-and-mice game” from the New York Times–bestselling author (William Bayer, Edgar Award–winning author). Karen is a lonely middle-aged doctor with a house in the woods. Sarah is a grief-stricken suburban widow who has turned to booze and barbiturates. Jordan is a directionless high school student and a child of divorce. They are three women with nothing in common but their red hair—until a stranger who calls himself the Big Bad Wolf sends each one the same chilling letter. Just like vulnerable Little Red Riding Hood, they are going to be stalked and killed—but in three distinct ways, in three different locations, all on the same fateful day. The one thing this devious madman didn’t count on was the Reds discovering each other. When authorities refuse to help, Karen, Sarah, and Jordan band together. But as they discover their power in numbers, how far are they’re willing to go to beat the Wolf at his own game. From the New York Times–bestselling author of Day of Reckoning comes a “twisted riff” on a Grimm tale (Publishers Weekly). “Must read for thriller fans.”—Booklist, starred review “Few writers of crime fiction seem to understand the criminal mind as well as Katzenbach.” —People
Taking On Tory Magic New Mexico Book 2 by S. E. Smith
New York Times and USA TODAY Bestselling author of Science Fiction, Urban Fantasy, and Paranormal Romance brings another action, adventure, and suspense-filled story to transport readers out of this world. Twenty-four year old Tory Carson is dying to get out of Magic, New Mexico and explore the world. She has spent her whole life cocooned in the protection of the close-knit community. When she finally gets a chance to go somewhere for three weeks, she would be crazy to say no. Even if her father is screaming it! Simon Drayton is a reclusive billionaire who has reinvented himself over and over again through the centuries. He has temporarily settled his headquarters in the beautiful city of Charleston, South Carolina. He is used to taking what he wants. He has learned that wealth and power are potent motivators for those who are greedy. Confusion reigns when he sets his sights on a beautiful, young female who is oblivious to his power. After centuries of getting what he wants, he is shocked, and just a little bit fascinated, when he discovers that not all things are for sale. Things heat up when the irritating, young ‘human’ woman refuses to play the game by his rules. She isn’t impressed with his wealth. She isn’t impressed with his looks. In fact, she acts like she isn’t impressed by anything he does, even when he flashes his teeth! Find out what happens when a centuries old Werewolf discovers he isn’t the only creature who loves to bite.
Her 2 by Robert Bazell
Two years after she underwent a mastectomy and chemotherapy, Barbara Bradfield's aggressive breast cancer had recurred and spread to her lungs. The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free. Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers. Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.