blood and loss
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|Author||: Michael F. Murphy,Derwood H. Pamphilon|
|Editor||: John Wiley & Sons|
This new edition of the comprehensive guide to transfusion medicine is now fully revised and updated. The Third Edition includes two new sections, one on alternatives to blood transfusion, and one on cellular and tissues therapy and organ transplantation. It focuses on clinical aspects but also covers background science and organizational issues. This timely volume highlights controversial issues and provides advice for everyday clinical questions in transfusion medicine. Practical Transfusion Medicine, Third Edition, is an essential manual for all those working in modern transfusion medicine.
|Author||: Alex Barclay|
FBI agent Ren Bryce takes on her most heart-wrenching case yet when a father's work places his young daughter in terrible danger... OUT OF SIGHT When a teenage girl is found beaten and raped in the grounds of a derelict asylum, FBI agent Ren Bryce is called in to assist. But she is soon diverted to a missing persons' case when an eleven-year-old girl and her teenage babysitter vanish without a trace from their hotel room. OUT OF MIND Faced with conflicting evidence and inconsistent witnesses, Ren works obsessively to unravel the dark family secrets at the heart of the case, before it's too late... OUT OF CONTROL Determined to uncover the truth, Ren's behaviour becomes increasingly reckless. Putting her own safety at risk, she enters a world where innocent lives are ruined for profit ... and kidnap, rape and murder are all part of the deal.
|Author||: Kerena Swan|
Sarah With one eye on the rear view mirror and the other on the road ahead, Sarah is desperate to get as far away from the remote Scottish cabin as she can without attracting attention. But being inconspicuous isn't easy with a black eye and clothes soaked in blood... ... and now the fuel tank is empty. DI Paton When a body is discovered in a remote cabin in Scotland, DI Paton feels a pang of guilt as he wonders if this is the career break he has been waiting for. But the victim is unidentifiable and the killer has left few clues. Jenna With the death of her father and her mother's failing health, Jenna accepts her future plans must change but nothing can prepare her for the trauma yet to come. Fleeing south to rebuild her life Sarah uncovers long-hidden family secrets. Determined to get back what she believes is rightfully hers, Sarah thinks her future looks brighter. But Paton is still pursuing her... ... and he's getting closer.
|Author||: Alex Barclay|
|Editor||: Delacorte Press|
In this electrifying thriller—a bestseller in Great Britain and Ireland—Alex Barclay creates a stunning array of contrasts—from the violence of a cop’s world to the fragility of an embattled marriage, from the danger of New York’s gritty streets to the quiet of a seaside Irish village. With brilliance and subtlety, Barclay delivers a nerve-wracking tale of a troubled family, facing a brutal danger rushing relentlessly out of the past. One year has passed since a kidnapping drama exploded into violence on a New York street. And for NYPD detective Joe Lucchesi, the memory of that terrible moment is still alive. Joe’s wife, Anna, has brought him and their teenage son to Ireland, hoping to repair their fragile marriage—and cut the cord between Joe and the job. But when the girlfriend of their son vanishes, Joe begins to suspect that the crime may have its roots in his old life—and that someone has followed him all the way there…. An outsider in Ireland, Joe watches with rising apprehension as local cops try to solve the disappearance—and then reacts with fury when his son becomes the leading suspect. Frantically, Joe tries to piece together clues to the crime, certain that a predator has come to Ireland in a twisted act of vengeance. And in a culture he doesn’t understand, among people who may or may not be his friends, Joe must find a way to strike back…against a vicious killer who has Joe’s family in his sights.... A novel that plunges like a knife, Darkhouse delves into the intimate struggles between a husband and wife, between lovers and desperate friends. Seething with menace and mounting dread, Alex Barclay’s ingenious tale of a family under siege ratchets up the suspense one shocking revelation at a time as it races to its shattering climax....
|Author||: Andrew B. Leibowitz,Suzan Uysal|
|Editor||: Cambridge University Press|
Close monitoring of patients during anesthesia is crucial for ensuring positive treatment outcomes and patient safety. The increasing availability of new technologies and the repurposing of older monitors means more patient data is at anesthesiologists' fingertips than ever before. However, this flood of options can be overwhelming. A practical resource for understanding this array of clinical monitoring options in anesthesia, this important text focuses on real-world applications in anesthesia and perioperative care. Reviewing the evidence for improved patient outcomes for monitoring technology, neurological monitoring, echocardiography systems and ultrasound are amongst the techniques covered in a head-to-toe approach. Statistics used by manufacturers to gain approval for their technology are discussed, as well as the under-appreciated risks associated with monitoring such as digital distraction. Future monitoring technologies including wearable systems are explored in depth. Focusing on applied practice, this book is an essential text for front-line healthcare professionals in anesthesia.
|Author||: WHO,World Health Organization,World Health Organization. Blood Transfusion Safety|
|Editor||: World Health Organization|
Summarises key information from the WHO learning module The clinical use of blood..
|Author||: Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst|
A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR
|Author||: Roland N. Pittman|
|Editor||: Biota Publishing|
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
|Author||: George Watts Newell|
|Author||: Marilyn J. Cipolla|
|Editor||: Biota Publishing|
This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
|Author||: Ulrich Franz Gruber|
|Editor||: Springer Science & Business Media|
The manifold problems of shock are still of great importance, diagnostic and therapeutic experience of the "severely ill" being supplied with new information almost every month. In the 5 periodicals which have found their way to my desk during the past few days there are no less than 10 interesting articles on questions concerning shock research [see Bibliography 41 b, 53 a, 60 a, 192 a, 242 a, 350 b, 810 a, 941 a, 1069 a, 1082 a]. The most urgent point still is to maintain as complete as possible the objective catalog of the various shock manifestations found in man and in animals - yet at the same time to view interpretations of these phenomena in their relative and temporal "truth". Problems of shock research are not only interesting for their scientific value but also for their clinical implication. In particular, almost every practicing physician is facing problems of blood replacement very frequent ly. The effective or circulating blood volume remains an important theoret ical and therapeutic problem in the shock field. For years, U. F. GRUBER has pursued this question clinically and experimentally. This volume deals with the world literature in an exceptionally thorough manner. This book is made more than a compilation by including a long list of original work done with F. D. MOORE in Boston, in the Surgical Department in Chur, with L. E. GELIN and S. E.
|Author||: Petra Seeber,Aryeh Shander|
|Editor||: John Wiley & Sons|
To reduce transfusion-related morbidity and mortality, it is recommended that an integrated approach to blood management is employed using all available tools to reduce a patient's exposure to donor blood. Meeting the need for a book covering the concepts of blood management as a trend towards multidisciplinary blood management, this new edition is an important resource, providing healthcare professionals with a tool to develop background knowledge in blood management, its organization, methods and tools. Practicing clinicians will be fully prepared to successfully start and run blood management programs.
|Author||: World Health Organization,World Health Organization. Blood Transfusion Safety|
|Editor||: World Health Organization|
A module of learning material designed for use in education and training programmes.